[Contact dermatitis due to dimethyl fumarate].
نویسندگان
چکیده
Dimethyl fumarate is a fumaric acid ester. It been used for some years to treat psoriasis and also as a preservative in desiccant sachets in the transport of furniture and footwear. Its irritant properties and sensitizing potential in contact with the skin were recently highlighted when it was implicated as the causative agent in 2 epidemics of severe acute eczema: sofa dermatitis in northern Europe and shoe dermatitis in Spain. The present article aims to guide dermatologists in the diagnosis and management of patients allergic to dimethyl fumarate. We review the clinical manifestations, results of patch tests, possible cross-reactions, and sources of exposure to dimethyl fumarate responsible for these skin reactions.
منابع مشابه
Correlation between lesion site and concentration of dimethyl fumarate in different parts of shoes in patients with contact dermatitis caused by dimethyl fumarate in footwear.
BACKGROUND Dimethyl fumarate (DMF) has been identified as being responsible for an outbreak of shoe contact dermatitis in Europe. All reported cases to date have involved the dorsa of the toes and the dorsa of the feet, sometimes in association with other areas. OBJECTIVES To establish a correlation between the site of the lesions and the concentration of DMF in different parts of the footwea...
متن کاملAllergic contact dermatitis to dimethyl fumarate in footwear.
Sample 1: insole from black boot 120 Sample 2: tissue lining leather of black boot 640 Sample 3: insole from red boot 11 Sample 4: tissue lining leather of red boot 1.3 or leather sofas and armchairs manufactured in China. This substance has a wide-spectrum biocide activity and it is contained in paper bags, and progressively it can evaporate and contaminate the leather, textiles, food, cosmeti...
متن کاملSensitization to dimethyl fumarate with multiple concurrent patch test reactions.
BACKGROUND Chairs and sofas imported from China to Europe were shown to contain dimethyl fumarate (DMF), a sensitizing, volatile chemical. Many of the sensitized patients also had positive patch test reactions to acrylates. OBJECTIVES To analyse the occurrence and strength of DMF sensitization and the appearance of concomitant reactions. METHODS Patch testing with DMF in concentrations of 0...
متن کاملAllergic contact dermatitis to shoes induced by dimethylfumarate: A new allergen imported from China.
BACKGROUND In the last two years several cases of severe contact dermatitis related to newly acquired sofas and armchairs originating from China have been published. The responsible allergen is dimethylfumarate (DMF), an extremely potent sensitizer and irritant found in sachets inside the furniture. Recently, cases of contact dermatitis related to shoes and riding helmets have also been describ...
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ورودعنوان ژورنال:
- Actas dermo-sifiliograficas
دوره 101 3 شماره
صفحات -
تاریخ انتشار 2010